Journal: PLoS ONE
Article Title: Genome-Wide Transcription Study of Cryptococcus neoformans H99 Clinical Strain versus Environmental Strains
doi: 10.1371/journal.pone.0137457
Figure Lengend Snippet: (A) Pairwise correlation matrix. Four C . neoformans strains (H99, H4, S48B and S68B) were compared. Two independent samples were prepared for each fungal strain. Rep1–2: replicates of samples. Numbers in the box represents correlation coefficient values among groups. Dark box: high correlation; light box: low correlation. (B) Gene expression heat map. Dendrogram represents the colour-coded expression levels of the significantly regulated genes. The groups of genes which showed differential expressions in H99 versus other strains were as indicated. Low levels in H99 category indicates the genes with low expression levels in H99 (green) but high expression in the environmental strains (red). In contrast, high levels in H99 category indicates the genes with high expression levels in H99 (red) but show low expression in the environmental strains (green). Hierachrical cluster was performed with Euclidean distance metric and Ward’s Linkage rule clustering. Colour range represents log 10 (FC) of the microarray intensities.
Article Snippet: The slide was washed and scanned on a High Resolution Microarray Scanner C-model (Agilent Technologies).
Techniques: Expressing, Microarray